Prothrombin

Introduction:

Prothrombin is one of the most important blood clotting factors. Its activity is controlled by many factors. In addition, many medications and other substances can affect prothrombin levels in the blood. For this reason, a blood test for prothrombin is one of the basic examination indicators for identifying various pathologies.

Basic data:

*Synonyms:* Prothrombin, PT

Coagulation factor is a complex globulin protein synthesized by liver cells (hepatocytes). In addition to the main (first) part, consisting of 74 amino acids, the protein contains an additional 8 peptides. The molecular weight exceeds 75 kilodaltons. Included in the group of coagulation factors. Participates in hemostatic function, and also plays a role in the process of oxidative phosphorylation in tissues: in platelets.

Has molecular similarity to a similar liver protein