Purkinje Cells

Purkinje Cells are large efferent nerve cells found in large numbers in the cerebellar cortex. The cell body is pear-shaped, from which many profusely branching dendrites arise, which form many synapses with other neurons and are directed to the surface of the cerebellum. A long axon, which originates from the base of the cell located deep in the cerebellar cortex (see figure), is directed through the white matter to the cerebellar nuclei, forming synapses with their neurons, as well as to the vestibular nuclei (ed.).



Purkinje cells are large efferent nerve cells present in large numbers in the cerebral cortex. They are pear-shaped and have many branching dendrites. Purkinje cells form many synaptic connections with other nerve cells and send their long axons to the surface of the brain.

Purkinje cells play an important role in the regulation of movement and coordination of movements. They receive information from receptors located in various parts of the body and transmit it to the cerebellum. The cerebellum, in turn, regulates movement and coordination using information received from Purkinje cells.

In addition, Purkinje cells are also involved in the regulation of balance and the vestibular system. They transmit information about body position and movement to the vestibular nuclei, which in turn regulate balance and coordination of movements.

Thus, Purkinje cells play a key role in regulating movement, balance, and motor coordination, and their function is important for maintaining healthy and normal brain function.



Purkinjet cells: functional significance in the cerebellum![picture](https://avatars.mds.yandex.net/get-tutor/1548979/9c5fe402-8b8a-41ba-a420-051d3d1ef576.png/orig) Purkinjet cells belong to efferent nerve cells and are found in a large amount of the cerebellar cortex in cerebral zones VII - X. The pear-shaped body of the cell is located inside the cortex next to the fibers of the molecular layer. The intracellular space of cerebellar cells is filled with glia. Numerous branched dendrites, formed by almost straight branching, extend from the cell body. Typically, the trunk of one dendritic tree merges into the trunk of another. The dendrites contain a large number of synaptic connections (up to 200 thousand), some of which go to the medullary tissue. The cell processes are surrounded by extensive synapses between the white matter of the cerebellar nucleus and the medial longitudinal blade of grass. Many spinocerebellar neurons do not synapse with Purkin cells.

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