Pyridostigmine (Rupdostigmine)

Pyridostigmine (Pupdostigmine): description, use and side effects

Pyridostigmine (Pupdostigmine) is a drug that is used to treat myasthenia gravis. This disease is characterized by skeletal muscle weakness that often occurs after increased physical activity and worsens towards the end of the day. Pyridostigmine is an anticholinesterase agent that increases the concentration of acetylcholine at the neuromuscular junction, thereby improving the contractile function of skeletal muscles.

Pyridostigmine can be given orally or by injection. Usually the initial dose is 30 mg orally every 3-4 hours, but the dosage may vary depending on the severity of the disease and the individual characteristics of the patient. Pyridostigmine reduces symptoms of myasthenia gravis, such as muscle weakness, fatigue, and difficulty breathing.

However, pyridostigmine may cause side effects such as nausea, vomiting, abdominal pain, diarrhea, and increased sweating and salivation. In addition, the use of pyridostigmine can cause convulsions, bradycardia, arrhythmia, hypotension, bronchospasm and allergic reactions.

The trade name of pyridostigmine is Mestinon. This medication is available by prescription only and should only be used under the supervision of a physician.

In conclusion, pyridostigmine (Pupdostigmine) is an effective drug for the treatment of myasthenia gravis. However, like any other medicine, it can cause side effects, so you must strictly follow your doctor's recommendations for dosage and use.



Pyridostigmine is a drug belonging to the group of anticholinesterases. It is used to treat myasthenia gravis. Pyridostigmine can be given orally as tablets or as an injection.

Possible side effects when taking pyridostigmine: nausea, vomiting, abdominal pain, diarrhea, increased sweating and salivation.

Pyridostigmine is marketed under the trade name Mestinon.