Radiosensitizers

Radiosensitizers are chemicals that increase the sensitivity of tissues to the effects of radiation. They are used in medicine to treat cancer and other diseases associated with metabolic disorders.

Radiosensitizers work by increasing the concentration of free radicals in tissues, which leads to the death of tumor cells. This can be achieved by enhancing oxidation processes, increasing the level of peroxides or reducing the activity of antioxidant systems.

One of the most common radiosensitizers is cisplatin. It is used to treat cancer of the bladder, ovaries and cervix. Cisplatin is also used to treat metastatic breast cancer.

Another radiosensitizing drug is gemcitabine. It is used in the treatment of lung, bladder, breast and prostate cancer. Gemcitabine is also used in combination with other drugs to treat brain tumors.

Another radiosensitizing drug is radium-223 dichloride. It is used in the treatment of prostate metastases. Radium-223 can also be used to treat breast and lung tumors.

However, despite the effectiveness of radiosensitization, it has a number of side effects. For example, cisplatin can cause damage to the kidneys, liver, and gastrointestinal tract. Gemcitabine may cause nausea, vomiting, and diarrhea. Radium-223 can cause radiation damage to bone marrow and peripheral nerves.

Therefore, before using a radiosensitizer, it is necessary to conduct a thorough examination and evaluate the risks and benefits of its use. In addition, it is necessary to monitor the patient's condition during treatment and adjust the dosage if necessary.