Ranitidine (Ranitidine)

Ranitidine is an antihistamine; suppresses the secretion of gastric juice. Used to treat gastric and duodenal ulcers, esophagitis and Zollinger-Ellison syndrome. Can be administered orally, intravenously or intramuscularly; possible side effects: headache, skin rash and drowsiness. Trade name: Zantac.

Ranitidine is an antihistamine that is used to treat various diseases of the gastrointestinal tract. It is a histamine H2 receptor inhibitor and works by inhibiting gastric acid secretion.

The main use of ranitidine is the treatment of gastric and duodenal ulcers, esophagitis and Zollinger-Ellison syndrome. The drug can be prescribed orally, intravenously or intramuscularly, depending on the severity of the disease and the doctor’s recommendations.

Ranitidine is well tolerated by most patients, but, like any other drug, it can cause side effects. Some of them include headache, skin rash and drowsiness. In rare cases, more serious side effects such as allergic reactions and liver problems may occur.

Ranitidine is available on the market under various trade names, including Zantac. It is important to remember that self-medication with ranitidine can be dangerous and should only be taken as directed by a doctor.

In general, ranitidine is an effective drug for the treatment of diseases of the gastrointestinal tract, and its use should be discussed with a doctor in each specific case.

The drug Ranitidine

Ranitinine, also known as Zantac, is a medicine used to prevent ulcers and gastritis and to control symptoms of chronic heartburn.

Ranitidine hydrochloride is a macrocyclic lactone derivative with inhibitory activity at histamine H2 receptors. In the gastrointestinal tract, it inhibits both basal and stimulated secretory activity of the glands. The degree of inhibition of parietal cells and the gastrin content in plasma may increase in the first days of treatment, and statistically significant individual fluctuations in these indicators are also noted. However, the degree of inhibition of antisecretory function when using the drug is in many cases very insignificant, and these changes do not affect the clinical effect of the drug. The histamine-blocking effect begins quickly and lasts for at least 24 hours. A special feature of the drug is the absence of suppression of GTP dinucleotide sequences in the binding of secretory components to membrane receptors of the parietal epithelium. As a result, the production of hydrochloric acid is not inhibited in the presence of mucopolysaccharide mucin in the gastric mucosa. Ranitidine also has a bactericidal effect against Helicobacter pylori (it acts on some strains by creating an unfavorable environment for their reproduction, which leads to stopping reproduction and weakening colonization of the stomach).

The targeted effect of the drug, manifested