Eisenmenger Reaction

The Eisenmenger reaction is a condition in which pulmonary hypertension is accompanied by a ventricular septal defect of the heart, which leads to the shunting of blood from the right ventricle to the left or from the pulmonary artery to the aorta. This causes oxygen-depleted, bluish-colored venous blood to enter the systemic circulation, bypassing the lungs. As a result, the oxygen content in arterial blood decreases, the patient develops cyanosis and the number of red blood cells increases (polycythemia).

There is currently no effective drug treatment for this condition. However, the patient may be prescribed medications to treat heart failure and polycythemia. The development of the Eisenmenger reaction can be prevented by promptly treating an existing septal defect before irreversible pulmonary hypertension occurs.

Eisenmüller reaction is a condition that occurs in pulmonary hypertension with a septal defect. In this case, blood from the right side of the heart or from the pulmonary arteries enters the aorta, and then into the general circulation. This causes oxygen-depleted blood to enter the body, causing cyanosis (blue color) and an increase in the number of red blood cells in the blood.

Although there is currently no drug treatment for Eisenmuller's reaction, there are medications that help treat heart failure and polycythemia.

However, it is important to remember that the development of this condition can only be prevented by treating the septal defect before irreversible pulmonary hypertension develops.

Eisenogger's reaction is a rare pathological condition characterized by high blood pressure that occurs due to lung disease and cardiac septal defects. As of 2018, only a few cases of EC have been officially reported in the world, most of which were post-mortem studies of bodies of people who died from heart disease. Among nearly a hundred scientific papers on the Eisenager reaction, only one is described in the context of a clinical case.