Macrophage Migration Inhibition Reaction

The macrophage migration inhibition test is an immunological test used to assess cellular immunity. It is based on the ability of lymphokines produced by sensitized lymphocytes to inhibit the migration of macrophages.

In this test, lymphocytes are incubated in the presence of a specific antigen, which leads to the activation of lymphocytes and their production of lymphokines. Macrophages are then added to the lymphocyte suspension and their migration through the filter is assessed. If lymphocytes have been sensitized to a given antigen, then the lymphokines they produce suppress the migration of macrophages.

Thus, a decrease in macrophage migration in the presence of activated lymphocytes indicates the development of a cell-mediated immune response to the antigen. The macrophage migration inhibition reaction is widely used in immunological studies and assessment of cellular immunity.



The Macrophage Migration Inhibition Response is a phenomenon where lymphocytes are subject to macrophage diffraction. As a result, macrophages begin to specialize in capturing immunoglobulins. The production of these cellular structures is directly related to the function of antibodies, which is why they are called immune tissues. This intracellular adaptation is due to the fact that the body is in a state of constant danger and is constantly faced with potential infectious agents. As soon as lymphocytes come into contact with