Extemporaneous compounding (from the Latin ex tempore - “according to the circumstances”) is the manufacture of medicines in pharmacies directly according to doctors’ prescriptions.
Extemporaneous formulation allows drugs to be produced taking into account the individual characteristics and needs of a particular patient. Unlike finished drugs produced by the pharmaceutical industry, extemporaneous drugs are produced in small quantities and strictly as prescribed by the doctor.
The production of extemporaneous dosage forms is carried out in specially equipped pharmacy premises under conditions that ensure their quality and effectiveness. For their production, pharmaceutical substances, excipients, solvents, necessary equipment and inventory are used.
Thus, extemporaneous formulation makes it possible to expand the range of medicines and provide an individual approach to patient treatment.
An extemporal recipe (from the Latin ex tempore “on occasion, as needed”) is a recipe that was compiled in advance, but then modified to suit specific conditions, circumstances or needs.
In medicine, extemporaneous formulation is used to prepare drugs that cannot be produced in the laboratory or require special storage conditions. Such prescriptions can be compiled by a doctor based on existing standard recipes, but taking into account the individual characteristics of the patient.
One of the main features of extemporaneous formulation is that it can be changed depending on the availability of certain ingredients or their availability. For example, if the pharmacy does not have a certain ingredient, the doctor can replace it with another that is currently available.
In addition, extemporaneous formulation can be used to create new drugs that have not yet been developed in the laboratory. This may be especially useful for treating rare diseases or helping in emergency situations.
One example of extemporal formulation is the creation of an influenza vaccine. In the past, flu vaccines were created in a laboratory by growing and purifying the virus, but the process was time-consuming and labor-intensive. However, thanks to extemporaneous formulation, scientists can quickly create new vaccines that can be adapted to changing strains of the influenza virus.
Thus, extemporaneous formulation is of great importance in medicine and other fields where rapid and flexible response to changes is required. It allows the creation of new medicines and vaccines in a short time, which can save lives and improve people's quality of life.