Rejection

Rejection is the process by which a person's body rejects a transplanted organ or tissue. This can happen if the organ or tissue is incompatible with the recipient's body or if the recipient's immune system cannot cope with the transplant.

In transplantation, rejection can result in loss of the transplanted organ or tissue and the need for a second operation. This can be life-threatening for the patient.

Various methods are used to prevent rejection, such as immunosuppressive therapy, selection of a suitable donor, and use of special transplant materials. However, sometimes rejection does occur, and in such cases, repeat surgery may be required.

Rejection is one of the most important aspects in transplantation practice, which affects long-term engraftment in recipients and can lead to complications and even death of the patient. This phenomenon occurs due to differences in the immune system of the recipient and the donor’s body, which leads to

Rejection of organ transplants after surgery.

Organ transplantation from person to person is performed when the material of donors and recipients is incompatible according to ABO factors. The donor organ acts as a foreign antigen for the owner, which causes a powerful immune response in the latter. The development of a reaction to a donor substance occurs due to antibodies, which appear as a result of the material entering the human body at any age. Maintaining organ health after unsuccessful transplantation becomes important. To improve the patient's condition, pharmacological drugs are used. The main stages of the immune response: - Presentation (the appearance of antigens occurs when they enter the bloodstream); - Formation of antigen-presenting cells from dendritic cells; - Resistance to tissues;

Rejection is the most severe and dangerous complication associated with organ and tissue transplantation in humans. It occurs from the first day after transplantation. The following symptoms appear: - Catarrhal manifestations; - Runny nose; - Fever;