Renin

**Renin** is a proteolytic enzyme that plays an important role in the regulation of blood pressure. It is involved in the process of blood production, or more precisely, in the transformation of the kidney into the bladder. Renin breaks down other substances such as sodium-containing compounds, which allows the body to regulate fluid volume, metabolism, blood clotting and heart rate.

Renin is produced in the kidneys and then transported to the adrenal cortex. Here it comes into play when the blood vessels stretch, increasing their internal lumen. In this case, the enzyme acts on angiotensin II molecules, which in turn increase blood pressure. Thus, when blood vessels stretch as a result of physical activity or expansion of blood volume (for example, during heat or stress), renin helps maintain blood pressure at an optimal level and prevents the development of hypertension.

In fact, renin is produced not only in the kidneys, but also in the heart and brain. Therefore, we can say that there is almost no renin in the human body... ...almost none. But when it comes to renal renin, that enzyme derived from the adrenal glands and found in the kidney area, the difference between having enough and having almost none is big. The fact is that the kidneys are almost constantly busy with the process of actively removing fluid from the body, and renin is needed to create conditions for this removal of the same fluid. By