Riboflavin (Vitamin B2)

Country of origin: Denmark, Roche Vitamins Ltd. Germany
Pharm-Group: Riboflavin group (vitamin B2)

Manufacturers: Basfhelff (Denmark), Roche vitamins Ltd (Germany)
International name: Riboflavin
Synonyms: Riboflavin
Dosage forms: substance-powder, substance 20g, substance 50g, substance 100g, substance
Composition: Active substance - Riboflavin.

Indications for use: Hypo- and ariboflavinosis of exo- and endogenous origin, hemeralopia, conjunctivitis, iritis, keratitis, corneal opacities, cataracts, long-term non-healing wounds and ulcers, radiation sickness, asthenia, cheilitis, angular stomatitis (jams), glossitis, itching dermatosis, eczema, neurodermatitis, photodermatosis, seborrhea, red acne, candidiasis, viral hepatitis A, chronic hepatitis, cirrhosis of the liver, gastrointestinal dysfunction, sprue, malnutrition, anemia, leukemia.

For preventive purposes - decreased absorption from the gastrointestinal tract, intensive elimination and increased need for riboflavin (acute and chronic hypoxia, respiratory and heart failure, burn disease, frostbite, protein deficiency and excess carbohydrate nutrition, acute infectious diseases, including during treatment antimicrobial agents that suppress gram-negative intestinal flora, phototherapy).

Contraindications: Hypersensitivity, nephrolithiasis.
Side effects: Visual impairment, kidney function, allergic reactions.

Interaction: Aminazine, imizin, amitriptyline disrupt (flavin kinase blockade) the incorporation of riboflavin into flavin mononucleotide, flavin adenine dinucleotide and increase its excretion in the urine.

When combined with thyroid hormones, metabolism accelerates. Under the influence of m-anticholinergics, absorption and bioavailability increase (due to slower intestinal motility).

Compatible with antianemic drugs, antihypoxants, anabolic steroids. Prevents or reduces the undesirable effects of chloramphenicol (disturbance of hematopoiesis, optic neuritis). Possible reduction in the activity of tetracyclines.

Overdose: No information.

Special instructions: Urine may turn yellow.

Literature:

1. Encyclopedia of Medicines, 2003
2. M.D. Mashkovsky "Medicines", ed. No14., Encyclopedia of Medicines, 2003

Action. Riboflavin is involved in the processes of protein, carbohydrate and fat metabolism, visual function of the eyes, and in the synthesis of hemoglobin.

Indications. Hypo- and ariboflavinosis, conjunctivitis, long-term non-healing wounds and sutures, radiation sickness, eczema. Botkin's disease and other liver diseases, dysfunction of the gastrointestinal tract. Iron-deficiency anemia.

Directions for use and dosage. Riboflavin is taken for preventive and therapeutic purposes. The daily requirement for vitamin B2 for an adult is about 2.5 mg. A single therapeutic dose for oral administration is 0.005-0.01 g (5-10 mg) per day for adults. For more severe cases - 0.01 g 3 times a day. Children are prescribed 0.002-0.005 g and up to 0.01 g per day, depending on age.

Release form. Tablets 0.002; 0.005 and 0.01 g. Riboflavin is part of multivitamin preparations (Aerovit, Kvadevit, Glutamevit, Complivit, etc.).