Focal sclerosis
Focal sclerosis (s. focalis) is a chronic progressive demyelinating disease of the central nervous system, characterized by multiple foci of demyelination in the brain and spinal cord.
With focal sclerosis, periodically appearing and disappearing foci of inflammation are observed in the white matter of the brain and spinal cord. These lesions lead to disruption of the conduction of nerve impulses. Over time, demyelination of nerve fibers occurs and neurological deficits develop.
The main symptoms of focal sclerosis: disturbances in vision, sensitivity, coordination of movements, speech, cognitive functions. The course of the disease is characterized by periodic deterioration (exacerbation) and temporary improvement (remission).
Diagnosis is based on analysis of the clinical picture, MRI data and cerebrospinal fluid analysis. Treatment includes immunomodulatory therapy to slow disease progression and symptomatic therapy. The prognosis depends on the course of the disease and the degree of disability.