Scopolamine

Scopolamine is an anticholinergic drug used to treat various diseases such as kinetosis, Meniere's disease, irritable bowel syndrome and others. This drug is also known as hyoscine, which is another of its trade names.

Scopolamine belongs to a class of anticholinergic drugs that block the action of acetylcholine, a neurotransmitter that transmits signals in the central and peripheral nervous systems. Blocking acetylcholine leads to muscle relaxation and decreased gland secretion, which may have a beneficial effect in patients with certain diseases.

One of the most common uses of scopolamine is to prevent and treat kinetosis, a condition that occurs with movement and causes symptoms such as nausea, vomiting, dizziness and loss of balance. Scopolamine helps prevent these symptoms by blocking acetylcholine signals in the ear canal and brain.

Additionally, scopolamine may be used to treat Meniere's disease, a chronic disorder of the inner ear that causes symptoms such as dizziness, nausea, and hearing loss. Scopolamine may help reduce symptoms and improve patients' quality of life.

Scopolamine may also be used to treat irritable bowel syndrome as it can help reduce intestinal smooth muscle spasms and improve intestinal motility.

Despite the positive effects of scopolamine, it does have some side effects such as dry mouth, difficulty urinating, blurred vision and psychomotor agitation. In addition, scopolamine may cause drowsiness, so patients should be careful when driving or operating machinery.

In general, scopolamine is an effective drug for the treatment of certain diseases associated with dysfunction of the nervous system. However, before using this drug, you should consult your doctor and evaluate the benefits and risks of its use in each specific case.

Scopolomine is the generic name for the drugs scopolamine male semitamine (seeds, leaves, root), scopolamine hydrochloride), also called scop or geoscine. The active substance is the alkaloid scopolamine amines, which is part of the group of atropine alkaloids (atropine, hyosmine). In addition, the group of atropine of plant origin includes oxyberine, pilocarpine, atropine sulfate, platiphylline, papaverine and some other substances.

SCOPOLAMINE is an obsolete name for amylobarbital.

The pharmacological action is carried out by blocking anticholinesterase mechanisms (including cholinesterase) of the central nervous system and inhibiting GABA-benzodiazepine receptors, which causes the development of central anticholinergic, muscle relaxant, antiepileptic, anxiolytic, sedative, hypnotic and narcotic effects. Its strength is inferior to phenobarbital and barbamyl.

Used in adults as a sedative-hypnotic for psychomotor agitation, anxiety, increased irritability, autonomic dysfunction, premedication before surgery and those suffering from severe somatic diseases, in children (newborns)