Sepsis of the Newborn

Sepsis of newborns is a severe infectious disease of newborns caused by the penetration into the body and generalization of pathogenic and opportunistic microorganisms.

Etiology and pathogenesis

The causative agents of sepsis are staphylococcus, salmonella, Escherichia coli and Pseudomonas aeruginosa, Klebsiella, Proteus, Listeria, etc. Infection of the fetus can occur ante-, intra- or postnatally. Risk factors are acute infections in the mother, obstetric manipulations, a long anhydrous period, and the presence of purulent foci in the mother. The gates of infection are often the skin, mucous membranes, and umbilical vessels.

Clinical picture

There are acute, subacute, protracted and fulminant courses. Clinical manifestations: intoxication, fever or hypothermia, neutrophilic leukocytosis, changes around the umbilical vessels. With septicopyemia, pyemic foci appear.

Diagnostics

The diagnosis is based on medical history, clinical picture, blood culture, and dysgammaglobulinemia.

Treatment

Broad-spectrum antibiotics, infusion therapy, detoxification, and, if necessary, surgical treatment are used.

Prognosis and prevention

Mortality reaches 10-20%. Prevention includes monitoring the course of pregnancy and preventing infection.

Neonatal sepsis is an infectious disease that occurs in newborns in the first days of life and can lead to serious complications. This disease is associated with the penetration of bacteria or viruses into the baby's blood through the umbilical cord or skin.

Neonatal sepsis can be caused by various bacterial infections such as Staphylococcus aureus, Group B Streptococcus, E. coli, etc. These bacteria can enter the baby's body through open wounds on the skin, the umbilical wound, or through the mother's blood during pregnancy.

Symptoms of neonatal sepsis may include fever, chills, sweating, headache, weakness, lack of appetite, and others. If neonatal sepsis is not treated promptly, it can lead to severe complications such as meningitis, pneumonia, sepsis and others.

Antibiotics and other drugs are used to treat neonatal sepsis. It is also important to provide the child with proper care and nutrition so that he can recover faster from illness.

Prevention of neonatal sepsis involves maintaining good hygiene, proper care of newborns, and vaccination against certain infections that can cause sepsis.

**Sepsis of a newborn** or neonatal sepsis (from Latin _sepsis_ - rotting, blood poisoning and -Latin _novus_ - newborn, child) is a dangerous infectious disease that can cause many problems with a person’s health for the rest of his life. When a newborn baby develops sepsis, this indicates the development of inflammation in the child's body due to the fact that infections are spreading through the blood. This can lead to serious consequences for the child, which in some cases can even lead to death.

Neonatal septic shock and persistent inflammation of wounds in a newborn are called fetal sepsis as a separate and extremely severe form of the disease.

Sepsis of newborns includes: * nosocomial infection (HAI), which most often affects children born prematurely or having any congenital developmental pathologies; * purulent mastitis,