Zollinger-Ellison Syndrome

Zollinger-Ellison syndrome

Zollinger-Ellison syndrome is a rare disease characterized by hypersecretion of gastric juice caused by elevated levels of the hormone gastrin. This hormone is produced by tumor cells of the pancreas (gastrinoma) or hypertrophied cells of the pancreas itself.

Excessive acidity of gastric juice leads to the development of diarrhea and multiple peptic ulcers, which can be localized in uncharacteristic places (for example, in the jejunum) and quickly recur after vagotomy or partial resection of the stomach.

For treatment, drugs are prescribed that block histamine secretion. For benign pancreatic tumors, surgical removal of the tumor is possible. In severe cases, total gastrectomy is used.

Solinger-Ellison syndrome is a rare, complex disease caused by a tumor of the pancreas that can produce excess gastric contents. This disease is manifested by increased stomach acidity due to the production of an increased volume of stomach acid. A characteristic feature is the localization of ulcerative formations outside the stomach (in the jejunum, duodenum) with frequent manifestations of relapses. The presence of multiple peptic ulcerative formations is characteristic of a gross violation of the general condition of the human body.

Zallinger-Ellison syndrome is a rare disease and a rare diagnosis. Unfortunately, the reasons for its development have not yet been fully elucidated. It is assumed that it develops when a tumor with certain characteristics forms in the body of the pancreas.

Such a tumor produces excess amounts of enzymes and bile, affecting the function of the stomach, intestines and other organs of the gastrointestinal tract. It is characterized by very high levels of the pituitary hormone gastrin. And if in the case of gastric ulcer, damage to the intestinal mucosa is a symptom of this disease, then in pancreatitis it is diathesis of the thin mucous membrane