Uricosuric Drug

Uricosuric Drug: mechanism of action and application

Uricosuric Drug is a medicinal substance that is used to treat gout and other diseases associated with high levels of uric acid in the blood. These substances help remove uric acid from the body, which reduces its concentration in the blood and prevents the formation of uric acid crystals in the joints and kidneys.

The mechanism of action of uricolytic drugs is that they block the reverse transport of uric acid in the renal tubules, which leads to its increased excretion in the urine. In addition, uricolytics can increase the excretion of acidic urinary nitrogen and creatinine, which helps improve kidney function.

Uricolytic agents, such as probenecid and sulfinpyrazone, are the main representatives of this group of drugs. They are usually prescribed in combination with a diet to reduce uric acid levels in the blood and other medications such as allopurinol, which blocks the body's production of uric acid.

The use of uricolytics may be effective in the treatment of gout and other diseases associated with high levels of uric acid in the blood, such as urolithiasis and hyperuricemia. However, before using these drugs, you should consult your doctor and become familiar with possible side effects, such as allergic reactions, impaired renal function and gastrointestinal tract.

In conclusion, uricolytic agents represent an important group of drugs for the treatment of gout and other diseases associated with high levels of uric acid in the blood. However, for effective treatment it is necessary to combine their use with diet and other medications, and also consult a doctor.

In this article we will look at the drug Uricolytic, which is used to treat diseases associated with high levels of uric acid in the body.

Uric acid is a substance that is formed as a result of the breakdown of purines contained in food. It plays an important role in metabolism and is necessary for the normal functioning of the body. However, under certain conditions, uric acid levels can increase, which can lead to various diseases such as gout, urolithiasis and others.

To treat these diseases, uricolytic drugs are used, which help remove uric acid from the body. One of the most common drugs is probenecid, which blocks the enzyme uricase, responsible for the formation of uric acid, and promotes its elimination.

Additionally, uricolytics may be used in combination with antibiotics such as penicillin to maintain high levels of uric acid in the blood. This is because antibiotics can slow down the process of removing uric acid from the body, which can lead to higher levels.

In general, uricolytics play an important role in the treatment of diseases associated with increased levels of uric acid in the blood. They help reduce symptoms and improve patients' quality of life. However, before starting treatment, you must consult your doctor and follow his recommendations.

Uricolytic agents are drugs designed to improve the metabolism of uricotic substances, helping to remove them from the body in urine. The use of uricolytics is necessary for disorders of amino acid metabolism, toxic liver damage, taking immunosuppressive drugs, oxalaturia, arterial hypertension caused by renovascular hypertension. In addition, they can be used for post-resection hyperuricemia, bedwetting, as well as in the complex treatment of hydronephrosis.