Stabizol HES 6%: Plasma replacement solution for restoring circulating blood volume
Stabizol HES 6% is a pharmaceutical drug belonging to the group of plasma replacement solutions based on gelatin, starch and albumin. It is produced in Germany by Berlin-Chemie AG and Menarini Group. The main active ingredient of the drug is hydroxyethyl starch.
Stabizol HES 6% is a solution intended for infusion. It is used in a variety of medical situations, including the prevention and treatment of hypovolemia and hypovolemic shock, especially in burns, trauma, surgery, septic conditions and other pathological conditions. It can also be used for hemodilution and increasing the collection of leukocyte mass by centrifugation during leukapheresis.
Despite its effectiveness, the drug has some contraindications. It is not recommended for hypersensitivity to the components of the drug, severe hemorrhagic diathesis, bleeding and coagulopathies. It should also not be used in case of hypervolemia, overhydration or dehydration, severe congestive heart failure, severe renal impairment, pregnancy, breastfeeding and in children under 10 years of age.
When using Stabizol HES 6%, some side effects may occur. Allergic and anaphylactoid reactions are possible, including urticaria, bronchospasm, pulmonary edema and heart failure. With large doses of the drug, coagulopathies, decreased levels of protein, albumin, calcium and fibrinogen in the blood, as well as increased amylase levels, may be observed. Other possible side effects include headache, dizziness, diarrhea, nausea, vomiting, temporary weight gain, restlessness, insomnia, feeling tired, weakness, malaise, fever, chills, trembling, swelling, paresthesia, acne, chest pain, increased palpitations, as well as a slight decrease in the number of platelets and hemoglobin levels.
The interaction of Stabizol HES 6% with other drugs has not yet been studied, so there is no data on possible interactions. There is also no information about cases of overdose of this drug.
When using Stabizol HES 6%, you must follow the instructions for use provided by the manufacturer or prescribed by your doctor. The dosage and rate of administration of the drug depend on the patient's medical condition and the requirements of the specific situation.
It is important to consult a medical specialist to obtain complete and accurate information about Stabizol HES 6%, its use, possible side effects and contraindications.