The protein-bound iodine test is one of the methods for studying the functional state of the thyroid gland. This method allows you to determine the content of iodine, which is bound to proteins in the blood serum.
Protein-bound iodides are a complex consisting of protein molecules and iodine. Normally, the human body contains a small amount of protein-bound iodine, but with pathology of the thyroid gland, the amount of this complex can increase significantly.
To test for protein-bound iodine, a radioimmunoassay method is used. In this method, radioactive iodine is added to the patient's blood serum, which binds to proteins containing iodine. The amount of radioactive iodine remaining in the serum is then measured, which allows the amount of protein-bound iodine to be determined.
The results of the protein-bound iodine test can be used to diagnose thyroid diseases and assess its functional state. For example, an increase in protein-bound iodine may indicate hyperthyroidism (overactive thyroid) or hypothyroidism (underactive thyroid).
In addition, the protein-bound iodine test can be used to monitor treatment for thyroid disease. For example, during radioactive iodine treatment, serum levels of protein-bound iodine can be used to assess the effectiveness of treatment.
Thus, the protein-bound iodine test is an important tool in the diagnosis and monitoring of thyroid diseases.
Test determination of bound iodine in protein
Abstract: The main indicator of impaired thyroid function is an increased level of hormones in the blood and tissues. Several biological processes are controlled by triiodothyronine binding protein. Which, in turn, can be used to assess the condition of the thyroid gland. An iodinated test system in young children with chronic illness and supplement use was associated with increased levels of triiodothyronine-bound protein.
Bound Protein Test Systems are a kit designed to quantify the presence of a biomarker-analyte molecule complex. Protein depot in a non-functional organ