Specific Histamine Release Test

The specific histamine release test (HSHT) is a method for identifying specific sensitization of the body and determining its intensity. This test is based on determining the amount of histamine released from a patient's white blood cells after adding a specific allergen to a cell culture.

TSSH is used to diagnose allergic reactions such as atopic dermatitis, bronchial asthma, urticaria and others. This method allows you to determine which allergens cause the most intense reaction in a particular patient and helps in choosing the most effective treatment.

To perform the TSSH test, a small amount of a specific allergen is injected into the patient, after which a sample of his blood is taken. The blood sample is then placed into a special cell culture that contains certain growth factors and factors that stimulate the release of histamine. As a result of this process, large amounts of histamine are released from the patient's blood cells, which can be measured using special devices.

The results of the TSSH test allow doctors to determine the intensity of a patient’s specific sensitization and choose the most effective treatment method. In addition, this method can be used to evaluate the effectiveness of treatment and monitor its effectiveness in the future.

Overall, the TSSH test is an important tool for the diagnosis and treatment of allergic reactions and other diseases associated with histamine-dependent reactions.

The Test for specific histamine release is a method for identifying specific sensitization (sensitivity) of the body, based on the in vitro release of histamine from the patient's blood cells. This test is used to diagnose allergic reactions and determine the body's sensitivity to certain allergens.

The essence of the test is to add a specific allergen to the patient's blood samples, which causes the release of histamine in the blood cells. If histamine levels increase in response to the addition of an allergen, this means that the body is sensitive to that allergen.

The specific histamine release test is performed in a laboratory and takes about 30 minutes. Before the test, the patient must prepare by eliminating food and drink 8-12 hours before the test.

This test is an important tool in diagnosing allergic reactions, allowing you to determine which allergens cause a patient's reaction and which of them may be harmful to health. The specific histamine release test can also be used to determine the effectiveness of treatment for allergic reactions.