Tetrahydrozoline

Tetrahydrozoline: constricts blood vessels to reduce swelling of the nasal mucosa

Tetrahydrozoline is a medicinal substance that is used to reduce swelling of the nasal mucosa. It belongs to a class of vasoconstrictors that cause blood vessels to constrict and thereby reduce swelling.

The narrowing of blood vessels occurs due to the effect of tetrahydrozoline on alpha-adrenergic receptors, which are located on the surface of the cells of the vascular wall. At the same time, capillaries and arterioles narrow, which leads to a decrease in the permeability of the vascular wall and a decrease in swelling.

Tetrahydrozoline is used to treat symptoms of a runny nose caused by an allergic reaction or a cold. It can be used as a symptomatic remedy to ease breathing and reduce the accumulation of mucus in the nasal cavity.

Tetrahydrozoline is available as nasal drops, gels, and sprays that are applied to the nasal mucosa. The dosage and frequency of use depend on the specific drug and are recommended individually by a doctor.

Despite its effectiveness, tetrahydrozoline may cause unwanted effects, including irritation and redness of the nasal mucosa, drying of the mucous membrane, headache, nausea and increased blood pressure. Therefore, before using tetrahydrozoline, you should consult your doctor and read the instructions for use.

In general, tetrahydrozoline is an effective and widely used vasoconstrictor for treating runny nose and reducing swelling of the nasal mucosa. However, like any other medicine, it must be used with caution and only as prescribed by a doctor.

Tetrahydrozoline is a drug that causes constriction of blood vessels, which leads to a decrease in swelling of the nasal mucosa and other tissues. It is widely used in medicine to treat various diseases associated with swelling and difficulty breathing.

The use of tetrahydrozoline dates back to the 1930s, when it was first developed to treat runny nose and other nasal conditions. Since then, it has become one of the most popular remedies for the treatment of swelling and nasal congestion.

The mechanism of action of tetrahydrozoline is that it blocks the receptors responsible for the dilation of blood vessels. This leads to vasoconstriction and reduced swelling. In addition, tetrahydrozoline may also have an antihistamine effect, reducing the level of histamine in the blood, which can cause tissue swelling.

One of the main advantages of tetrahydrozoline is its fast action. It begins to work within minutes of application and provides symptom relief for several hours. In addition, it is not addictive and can be used for a long time without side effects.

However, like any medicine, tetrahydrozoline has its contraindications and side effects. It can cause dry nose, irritation of the mucous membrane, headache, drowsiness and other undesirable reactions. Therefore, before using tetrahydrozoline, you should consult your doctor and follow his recommendations.

Overall, tetrahydrozoline is an effective treatment for nasal swelling and congestion, and its use can be justified when used correctly and under medical supervision. However, it should be remembered that self-medication can lead to serious consequences and complications, so you should always contact a specialist to receive qualified medical care.

Tetrahydrozonine hydrochloride or simply tetrahydrozoline (Tetrahydron) is a drug for topical use in the nose in the form of a 0.5% solution. Included in the list of Vital and Essential Drugs. The effect occurs within a minute after instillation. Duration of action is 5-6 hours. After using the drug, the blood supply to the mucous membrane of the nasal septum decreases and swelling of the palate decreases, as a result of which nasal breathing becomes easier and the amount of nasal discharge decreases.

Tetrahydrosaline is structurally similar to pseudoephedrine. Unlike all other alpha agonists, it does not stimulate the sympathoadrenal system and does not increase blood pressure. The effect occurs within a few minutes when instilled into the nasal cavity. Effective for sinusitis. Reduces swelling of the mucous membrane due to the fact that it causes constriction of peripheral vessels. May cause reflex bradycardia. Does not have a sedative, anticholinergic or prolactin-like effect. It is used mainly in the supine position, with the head thrown back slightly to the side. The therapeutic effect is equivalent to subsequent spontaneous breathing. The maximum concentration is set at 30 minutes after administration, the effective concentration is approximately 9 mcg/ml. Serum clearance (CL) ranges between 0.45 and 2.3 L/h. Css is achieved after just one dose; on average, the equilibrium state occurs after approximately 12 days, depending on the time of day. T1/2 of plasma is about 1-1.5 hours. If the solution is injected into the nasal passage, its duration of action increases to 6-8 hours; with intranasal use in a lying position when tilting the head back, intraocular pressure increases.