Thrombocytosis

Thrombocytosis: causes, symptoms, diagnosis and treatment

Thrombocytosis, also known as erythrocytosis, is a condition in which the number of platelets (platelet mass) in the blood is higher than normal levels. The normal level of platelets in the blood ranges from 150 to 450 thousand cells per microliter of blood. With thrombocytosis, this amount can exceed 450 thousand, which is the main reason for the increased tendency to form blood clots inside blood vessels (thrombosis).

Causes of thrombocytosis:
Thrombocytosis can be caused by a variety of diseases, including infectious, inflammatory, malignant tumors and blood diseases such as myeloproliferative diseases. Thrombocytosis can also be caused by taking certain medications, such as corticosteroids and epinephrine.

Symptoms of thrombocytosis:
Symptoms of thrombocytosis may be subtle or nonspecific, but in more severe cases may include headache, dizziness, visual disturbances, bleeding, hemoptysis, bruising of the skin, swollen lymph nodes, fatigue and weakness.

Diagnosis of thrombocytosis:
Diagnosis of thrombocytosis includes a complete blood test, which allows you to determine the number of platelets in the blood, as well as other parameters of the blood condition. If you have thrombocytosis, your doctor may order additional tests, such as a bone marrow biopsy or genetic tests, to look for a possible cause of the condition.

Treatment of thrombocytosis:
Treatment for thrombocytosis depends on the cause of the condition. If thrombocytosis is caused by medications, your doctor may stop taking those medications or change them to different ones. If the cause of thrombocytosis is associated with a disease, then treatment should be aimed at treating the underlying disease. In some cases, a therapeutic phlebectomy may be necessary, a procedure that removes excess platelets from the blood.

In conclusion, thrombocytosis is a condition in which the number of platelets in the blood is higher than normal. This condition can be caused by various diseases, including malignant tumors and blood diseases. Symptoms of thrombocytosis may be nonspecific, but in more severe cases may include bruising of the skin, swollen lymph nodes, bleeding, and hemoptysis. Diagnosis of thrombocytosis includes a complete blood count, as well as additional tests to determine the possible cause of this condition. Treatment for thrombocytosis depends on the cause of the condition and may include stopping medications, changing medications, treating the underlying condition, or performing a therapeutic phlebectomy. If you suspect thrombocytosis, you should see your doctor for diagnosis and treatment. In turn, maintaining a healthy lifestyle, proper nutrition and physical activity can help prevent various diseases, including those associated with thrombocytosis.

Thrombophilia is a common cause of thrombosis and is associated with an increased risk of cardiovascular disease. The main group of hereditary forms is hypercoagulable dysfibrinogenemia, in which the production of plasma fibrinogens with the walls of blood vessels is constantly reduced or the interaction of fibrinogens with the walls of blood vessels is impaired, which leads to a general increase in blood coagulability and intravascular thrombogenesis.

There may be a history of thrombosis in patients under the age of 50 years or at an even younger age. When assessing familial thrombotic risk, it is necessary to take into account the presence of thrombotic episodes in first-degree relatives (in young and old