Uranic acids are acids that are widely used in medicine. They are an important component of various medications, such as antibiotics, antitumor and antiallergic drugs.
Uranic acids were first discovered in urine resins at the end of the 19th century, but their chemical nature was established only at the beginning of the 20th century. These acids are uracil derivatives (UA), containing in their molecule two different types of electron-donating groups - carboxyl and hydroxyl.
The main part of uranium acids found in nature is associated with an organic substance - gallic acid pyrogallolate. At the same time, uranium acids of natural origin are poorly soluble in water and are easily oxidized, so they are most often obtained by synthesis from uracil.
Already at the turn of the 19th-20th centuries, the first uranium antibiotics were discovered - for example, uramycin from Streptomyces neonensis and streptomycin, produced by the same microbe Streptomyces, but found in the soil after the start of active research on the search for antibiotics. Over the course of further research, many antibiotics were discovered that contain uranium nuclei, and many pharmaceuticals based on uranium-like acids have now been created.
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