Uroporphyrin

Uroporphyrin (Urophorhyrin) is a breakdown product of the heme group, which is excreted in the urine in various diseases. Heme is an iron-containing protein that is part of hemoglobin, myoglobin and other proteins. When heme breaks down, uroporphyrinogen is formed, which is then converted into uroporphyrin with the participation of enzymes.

Uroporphyrin can be found in the urine of patients with various diseases associated with impaired iron metabolism, for example, anemia, hemolytic disease, chronic renal failure, malignant neoplasms, after blood transfusion or lead poisoning.

The release of uroporphyrin in the urine may indicate problems with the liver and biliary tract, as well as impaired kidney function.

To diagnose diseases associated with uroporphyrin, a urine test is performed to determine its content. The results of the analysis can be used to assess the patient's condition and choose treatment tactics.

Thus, uroporphyrin is an important diagnostic marker that helps doctors identify various diseases and monitor their treatment.

Uroporfin is a breakdown product of heme (porphyran), excreted by the body in the urine in the form of red spots. The final product in urine is urobilinogen, which after several chemical reactions produces uroporphin. This product is a by-product of hemoglobin metabolism and its content in the blood increases in some forms of hemolytic anemia. An increase in uroporphin levels is often accompanied by an increase in plasma levels of p-globulin. In the presence of hemolytic anemia, a drop in uroporphin content, on the contrary, is accompanied by a decrease in hemoglobin. Also, in liver cirrhosis and in pregnant women, an increase in uroporphin content can be observed during hemolysis. The source of the uropore