Pendinsky ulcer

Peninsky ulcer (from Latin ulcus - ulcer, pen - pus) is a deep foamy swelling of tissues, which manifests itself in the form of a fistula with purulent contents from the opposite end and a scar along the edge (Peninsky scar).

The occurrence of Peninsky ulcer is associated with penetration through the skin of the G-antigenic strain of M. vulgaris, the causative agent of cholera. In addition, sensitization of the body, formation of IgA antibodies, phagocytosis and hyperproduction of interferon by histiocyte cells, macrophages, and lymphocytes occur. These processes trigger the formation of deep foamy ulcers Peninskaya and Rubtsova, thinning of the walls of the stomach and intestines. Moreover, changes in the gastrointestinal tract occur both with localized and widespread forms of bacterial carriage. The severity of the reaction depends on the number and properties of microbes. The concentration of staphylococcus in the lumen of the stomach correlates with the severity of changes in the mucous membranes, which was proven experimentally using E. coli in animals.

Today, Peninsky ulcer is considered exclusively as a manifestation of an infectious pathology or a pronounced syndrome, and in clinical studies it is considered as the most accurate sign of infection with M. co.

According to statistics, Peninsky ulcer occurs in 25% of cholera patients, and in children its incidence is 3 times higher than in adults. Penia ulcers most often occur in adolescents aged 7 to 14 years. Unlike other forms of parasitic infection, M. peninsky type is not transmitted to the fetus during pregnancy.

Inflammatory reactions of various organs occur in approximately 50% of infected patients three weeks after infection with M. g. strains; in 90% in the fifth week. Clinical manifestations of Peniya ulcer most often begin one to two weeks after the microbe enters the human body.

More often, Peninsky ulcers occur in childhood: their hypersecretion processes are aggravated