Acropigmentation Matsumoto

Matsumoto Acropigmentation - This is also known as Komaya–Toyama or Symmetrical Acropigmentation. This is a rare genetic disorder characterized by symmetrical hyperpigmentation on the tips of the fingers and toes. The cause of the disease is a mutation in the KIT gene, leading to impaired migration and differentiation of melanocytes. Clinically manifested from early childhood in the form of brown spots on the pads of the fingers, sometimes also on the feet and palms. The spots usually do not progress over time. There are no other symptoms. The diagnosis is made based on the clinical picture. Treatment is not required as the disease does not pose a threat to health.