Acute Adrenal Cortex Insufficiency (Addisonian Crisis)

The adrenal glands are small paired organs located above the kidneys. Their main task is to produce hormones that regulate all vital processes. Acute adrenal insufficiency (Addisonian crisis) is a dangerous condition due to a sharp decrease in the production of these hormones.

Causes

Addisonian crisis often develops in chronic adrenal insufficiency if the patient stops taking replacement hormones. Other causes may include injuries, surgeries, infections, and impaired blood supply to the adrenal glands.

Symptoms

The condition quickly worsens: blood pressure drops, the functioning of the heart and kidneys is disrupted, vomiting and abdominal pain appear. Loss of consciousness and coma then develop.

Diagnostics

The diagnosis is confirmed by blood tests (decreased sodium, increased potassium and creatinine) and a study of the level of adrenal hormones.

Treatment

Urgent hospitalization and administration of corticosteroids is required. With timely treatment, the prognosis is favorable.

Prevention consists of adequate replacement therapy and regular monitoring by an endocrinologist. You cannot change the dosage of medications on your own.