Adalat Sl

Adalat SL is a drug that belongs to the group of calcium channel blockers of the dihydropyridine group. The active substance of the drug is nifedipine, which helps lower blood pressure and dilate the blood vessels of the heart. Adalat SL is available in the form of retard tablets 20 mg and rapid retard tablets 20 mg.

The drug is manufactured by Bayer AG in Germany. Adalat SL is widely used for the treatment of arterial hypertension, hypertensive crisis, prevention of angina attacks (including Prinzmetal's angina), hypertrophic cardiomyopathy (obstructive and other forms), Raynaud's disease, pulmonary hypertension and broncho-obstructive syndrome.

However, before using Adalat SL, you must familiarize yourself with the contraindications and restrictions for use. The drug is not recommended for use in case of hypersensitivity to its components, acute period of myocardial infarction (in the first 8 days), cardiogenic shock, severe aortic stenosis, heart failure in the stage of decompensation, severe arterial hypotension, tachycardia, pregnancy and breastfeeding.

When using Adalat SL, side effects may occur, which can manifest themselves in the cardiovascular system and blood, nervous system and sensory organs, gastrointestinal tract, respiratory system, musculoskeletal system, allergic reactions and others.

Also, you should pay attention to the interaction of Adalat SL with other drugs. Nitrates, diuretics, beta-blockers, tricyclic antidepressants, fentanyl and alcohol can enhance the hypotensive effect of the drug. Nifedipine may increase the activity of theophylline, reduce the renal clearance of digoxin, increase the side effects of vincristine and increase the bioavailability of cephalosporins (cefixime). Cimetidine and ranitidine may increase plasma levels, and diltiazem will slow metabolism (requires reduction of nifedipine dose). Incompatible with rifampicin (accelerates biotransformation and does not allow creating effective concentrations). Grapefruit juice (large quantities) increases bioavailability.

In conclusion, Adalat SL is an effective drug for the treatment of arterial hypertension, angina pectoris and other cardiovascular diseases. However, before starting to use the drug, you must familiarize yourself with the contraindications and restrictions for use, and also make sure that there is no interaction with other medications that are already being taken. Do not exceed the recommended dose and stop taking the drug without consulting your doctor. If any side effects occur, seek medical attention immediately.