Favalli-Hirschsprunga Disease

Favalli-Hirschsprung disease is a rare congenital disorder characterized by the absence of nerve cells (ganglia) in the wall of the colon. This leads to impaired peristalsis and stool retention in the affected parts of the intestine.

The disease was first described by Danish pediatrician Harald Hirschsprung in 1886. The cause of the disease is a mutation in the genes responsible for cell migration in the embryonic period.

Clinically manifested by constipation, bloating, vomiting in the first months of a child’s life. Diagnosis is based on x-ray and histological examination. Surgical treatment involves removing the affected area of ​​the intestine. The prognosis is generally favorable with timely treatment.