Pituitary adenoma Acidophilic

Adenoma is the most common pituitary tumor in humans. They can be classified according to various criteria such as size, morphology, and degree of histological differentiation and aggressiveness. One common type is acidophilus adenoma (AGA). This type of tumor is characterized by cellular heterogeneity and infrequent bleeding, making it more difficult to diagnose than other types of adenomas.

AGA is smaller and denser in structure than larger tumors. These tumors are acidic and more differentiated, meaning they are less aggressive but may present with complications such as headache, blurred vision and gonadal dysfunction. AGA may also have a better chance of success with treatment.

Originally, AGA was known as type C histiocytoma. Currently, this disease is known as acid-type histiocyte adenoma (adenoacidsis). It contains degenerated glial cells, mainly of neural origin, which secrete growth hormone. This hormone is caused due to overstimulation of hypothalamic groups of neurons and has no physiological basis. Adenomas grow slowly and do not appear in any way in the early stages. Symptoms may only appear when the tumor grows large and causes compression of surrounding structures or irradiation of the craniopharynx (cranial nerves). The most common symptoms are: hyperprolactinemia, which leads to infertility in women and erectile dysfunction in men; increased levels of growth hormone, also called acromegaly; this usually leads to an increase in the size of the torso, face and limbs, as well as a reduction in teeth; gigantism. This condition is caused when too much growth hormone causes tissue and bones to grow; a decrease in the level of thyroid-stimulating hormone, causing an enlargement of the thyroid gland; in

Ac. GP adenoma is a rare GP pathology (up to 5% of all adenomas) - a benign neoplasm, which is based on cells containing many ribosomes, where there is a high activity of cAMP synthesis. Changes the endocrine function of this hormone-producing gland. (ACTH, prolactin, TSH, STH-SG) It is always located either in the area of ​​the sella turcica, or has a “droplet” localization in the spongy substance, since it is in these areas of the pituitary gland that the vascular network is well developed .. The main sign is the presence of a large