Amniotic Plaques

Amniotic plaques are flat, whitish formations on the fetal surfaces of the amnion that occur with squamous metaplasia of the amnion. They have a diameter of 1-2 millimeters and are one of the signs of the development of amniotitis, which can lead to premature birth or other pregnancy complications.

Amniotic plaques form due to disruption of the normal process of migration of amnion cells through the amniotic fluid. As a result of this process, amnion cells accumulate in certain places, forming plaques. These plaques can be associated with various factors, such as infections, inflammatory processes, trauma, hormonal imbalances and others.

Symptoms of amniotic plaques may include abdominal pain, vaginal discharge, and changes in bowel and bladder function. There may also be changes in the amount of amniotic fluid and signs of infection.

If amniotic plaques are left untreated, they can lead to complications such as premature birth, fetal growth restriction, infections, and even fetal death. Treatment for amniotic plaques depends on the cause and may include antibiotic therapy, surgery, or other treatments.

It is important to remember that amniotic plaques are a sign of the development of amniotitis and require timely treatment. If you suspect amniotic plaques, you should see a doctor for diagnosis and treatment.

An amniotic plaque is one of the types of neoplastic process (neoplasm) in a woman’s body. It is distinguished by a rather rare nature of development and a specific manifestation. To put it simply, amniotic plaque is a bad condition associated with a change in the normal structure and properties of the amnion layer.

A local plaque is a flat white plaque, which is an absolutely safe formation for a child. The diagnosis is made if the diameter of the plaques is less than 2 centimeters. Standard dimensions can be from 3 mm. If large plaques are identified, it is necessary to determine the cause of their appearance and timely treatment.

Reasons for education! The formation of plaques is associated with the appearance of certain unfavorable factors in the developing fetus. Possible causes of development can be divided into 4 large groups: * toxic factor; * infections and viruses; * hypoxia (of the fetus); * circulatory disorders. Basically, the formation of plaques occurs with the first type of damage. Most often this occurs due to a toxic-chemical factor. The phenomenon is associated with a pregnant woman taking certain medications.

There are often cases of exposure of the fetus to cyto-burning drugs or anti-tuberculosis drugs. The most common effect in children is isoniazid, streptomycin or iron-containing glucosaminides. In total, in this case, the child receives up to 13-15 percent of substances that promote the formation of plaques on the amnion. After birth, the disease may not manifest itself in the future. The pathology does not give any complaints from the mother or outwardly obvious signs.

Amniotic plaques indicate respiratory or cardiovascular disorders on the part of the baby. The epithelium of such formations is dangerous primarily because it is capable of quickly transitioning from active processes to passive ones. At the same time, the processes of differentiation in them slow down significantly. Transformational Dileufbo syndrome occurs (the rate of development slows down).

With long-term plaques on the surface of the chorion, processes of villous atrophy often begin. Over time, characteristic features of the structure of derivatives of the chorionic epithelium are noted: * the presence of actively growing villi and hyperplastic chorionic structures; * deviation from the growth of foci of atrophy inside the amnion; * loosening of areas that arise from chorionic epithelial cells; * development and active formation of small and large areolas; * change in color of the amnion - from transparent to yellowish-gray; * change in the density and depth of focal formation structures. Such processes quickly lead to its interruption, after which the fetus begins to be born with acute defects, often incompatible with life. Among the main morphological processes during the development of amnionic plaques it is worth highlighting:

- active growth of the outer layer of polygonal cells. This formation covers the amnion around and completely surrounds the locus with the fertilized egg. Each subsequent layer includes in its structure an increasing number of protoplasts with already rudimentary places for the formation of a cell circle; - leukocyte infiltration. This includes red blood cells with a sharp predominance over leukocytes.