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Country of origin: Bulgaria
Pharm-Group: Antiallergic drugs

Manufacturers: Farmakhim (Bulgaria)
International name: Cromoglicic acid
Synonyms: Intal, Ifiral, Cromo, Cromohexal, Cromohexal Combi, Cromogen inhaler, Cromogen light breath, Cromoglin, Cromoglycin-Ratiopharm, Cromolyn, Cromosol, Kropoz, Kuzikrom, Lecrolin, Lomuzol, Nalkrom, Nalchrome, Opticrom, Thaleum, High chrome
Dosage forms: dosed aerosol for inhalation 15g, eye drops 2%, solution for inhalation, solution for inhalation 20mg

Composition: Active substance - cromoglycic acid.

Indications for use:
Capsules: food allergy (with proven presence of antigen), as an adjuvant: nonspecific ulcerative colitis, proctitis, coloproctitis, mastocytosis.
Eye drops: conjunctivitis (acute and chronic allergic, spring), keratitis and keratoconjunctivitis, dry eye syndrome, eye strain and fatigue caused by allergic reactions (environmental factors, occupational hazards, household chemicals, cosmetics, ophthalmic dosage forms, plants and pets).
Nasal spray: year-round and seasonal allergic rhinitis, hay fever.
Inhalation forms: bronchial asthma, including atopic, physical exertion and asthmatic triad, chronic bronchitis with broncho-obstructive syndrome. In the treatment of proctitis and coloproctitis, the drug Nalcrom can be administered in the form of microenemas.

Contraindications:
Hypersensitivity (including to benzalkonium hydrochloride), pregnancy, breastfeeding, children under 2 years of age (for metered dose aerosol - up to 5 years). Restrictions on use: presence of polyps in the nasal cavity (for intranasal forms).

Side effect:
For inhalation use:
From the skin: exanthema, dermatitis; rarely - urticaria; in some cases - vascular edema, photodermatitis, exfoliative dermatitis.
From the nervous system and sensory organs: in some cases - malaise, dizziness, irritability, insomnia, hallucinations, tremor, peripheral neuritis, tinnitus.
From the gastrointestinal tract: nausea, gastroenteritis; in some cases - unpleasant taste in the mouth, stomatitis, glossitis, swelling of the parotid salivary gland, esophagospasm, dyspepsia, flatulence, abdominal pain, diarrhea, constipation, impaired liver function.
From the genitourinary system: frequent urination, nephropathy.
From the respiratory system: bronchial irritation during inhalation (cough, retching, short-term spasm; rarely - expressed with a decrease in external respiration, requiring discontinuation of the drug), pharyngitis; very rarely - hemoptysis, laryngeal edema, eosinophilic pneumonia.
From the cardiovascular system: in some cases - chest pain, periarterial vasculitis, heart failure, pericarditis, hypotension, cardiac arrhythmia.
From the musculoskeletal system: myositis, in some cases - muscle and joint pain, polymyositis, joint swelling.
Other: rarely - serum sickness.

When taken orally:
From the gastrointestinal tract: nausea, vomiting, abdominal discomfort, diarrhea.
Other: skin rash, joint pain.

For intranasal administration:
From the gastrointestinal tract: unpleasant taste in the mouth, swelling of the tongue.
From the respiratory system: short-term irritation of the mucous membrane and increased secretion from the nose; very rarely - nosebleeds, ulceration of the nasal mucosa, cough, suffocation.
Other: headache, arthralgia, anaphylactic reaction (cough, difficulty swallowing, itchy skin, swelling of the face, lips or eyelids, difficulty breathing), exanthema, urticaria.
For ch.