Bilirubin

Bilirubin is one of the pigments of bile, which is formed as a result of the destruction of hemoglobin, the main component of red blood cells. Bilirubin is usually produced in the bone marrow, liver and spleen. Once formed, bilirubin binds to blood proteins and is transported to the liver, where it is processed and released into bile.

Bilirubin can be present in the blood in two forms: direct and indirect. Indirect bilirubin is not bound to proteins and is not soluble in water, so it can penetrate tissue and cause cell damage. Direct bilirubin, on the other hand, is bound to proteins and is soluble in water, so it is easily excreted from the body through urine and feces.

The normal level of bilirubin in the blood of adults is up to 1.2 mg/dL, and any deviation from this level may indicate the presence of liver disease, biliary tract disease, or other medical conditions. High levels of indirect bilirubin may be associated with hemolytic anemia, and elevated levels of direct bilirubin may indicate the presence of gallstones, hepatitis, or cirrhosis.

Bilirubin levels are measured using blood from a vein, and doctors usually recommend not eating or drinking for 8 to 12 hours before the test to get accurate results. If bilirubin levels are elevated, your doctor may order additional tests or procedures to determine the cause of the increase.

In conclusion, bilirubin is an important bile pigment that is formed from the destruction of red blood cells. High bilirubin levels can indicate the presence of liver or bile duct disease, and measuring it can help doctors identify health problems and prescribe appropriate treatment.

Bilirubin is a yellow pigment synthesized in liver cells from hemoglobin. Participates in the regulation of cell growth and reproduction, and also protects the body from infections. One of the first signs of increased bilirubin levels is the yellowness of the proteins of the skin, mucous membranes of the eyes, and sometimes fingers and toes, which is one of the possible manifestations of diseases of the liver and thyroid gland. The higher the bilirubin level, the more noticeable the pigmentation. In addition, it is possible to change the shade of the skin, often acquiring a brownish tint on the face, arms and legs. A person exhibits unhealthy pallor of the skin. This type of patient visually creates the impression of a flu-like illness.