Caffeine and other xanthines (theophylline, aminophylline): how they affect the body and what to do in case of overdose
Caffeine and other xanthines, such as theophylline and aminophylline, are popular psychoactive substances that can have powerful effects on the body. Although they are widely used medicinally to treat asthma and other conditions, in high doses they can cause serious side effects, including seizures, hypotension and abnormal heart rhythms.
The selective psychotropic, neurotoxic (convulsive) effect of caffeine and other xanthines occurs due to their ability to block adenosine receptors in the brain. This can lead to increased levels of neurotransmitters such as dopamine and norepinephrine, which contribute to increased nervous system activity.
However, if an overdose of caffeine and other xanthines occurs, serious side effects can occur. The first symptoms of an overdose may include tinnitus, dizziness, nausea, vomiting, fever and palpitations. In more serious cases, depression of consciousness up to a stuporous state, severe tachycardia accompanied by hypotension, cardiac arrhythmias and clonic-tonic convulsions may develop.
If you suspect an overdose of caffeine or other xanthines, you should consult a doctor immediately. Treatment may include gastric lavage through a tube, saline laxative and activated charcoal. In case of severe intoxication, forced diuresis or hemosorption may be required. Aminazine, lytic mixture, or diazepam may be used to reduce seizures and eliminate other side effects.
In conclusion, caffeine and other xanthines may have beneficial effects on the body in small doses, but in large quantities they can cause serious side effects. In case of overdose, you should immediately consult a doctor for help.