Erythroblastosis

Erythroblastosis is a rare hereditary blood disease manifested by hemolytic anemia and erythroid metaplasia in the bone marrow, which leads to the formation of immature red blood cells - erythroblasts.

Erythroblastosis occurs as a result of a metabolic disorder, which leads to underdevelopment of one of the forms of red blood cells, which is called promyeloblast. These defects cause the disease to be hereditary, meaning they appear in certain people and are not passed on to children. This disease became known when in 1912 the British physician Jameson and his colleagues reported 4 cases of fatal erythrolysis.