Flexnera Dysentery

Flexner's dysentery, or s. flexner is a disease that is caused by the bacterium shigella flexneri and is characterized by the development of diarrhea, abdominal pain, vomiting and other symptoms. Flexner's dysentery is one of the most common infectious diseases in the world, especially in developing countries.

**Occurrence and transmission of the disease** Flexner or Shigella Flexner (Shigella dysenteriae) dysentery, the causative agent of which is Shigella Flexner or Salmonella Flexna, has been known since ancient times and has been causing severe epidemics in humans for many centuries. Most often, with this disease, a person becomes infected through animal feces, but it can also become infected from a person through contact with their feces or contaminated products. Infection is less likely through water, food or other shared objects. In this case, a bacteriological vaccine is produced from the affected Shigella, which is used for prevention.

Shigella Freinser is the causative agent of dysentery and pseudomembranous colitis - these diseases in humans. They can be found in large quantities in the patient’s feces in the first days of illness, but their presence in food products does not portend a danger to human health. Under high magnification they can be detected on fruits. Currently, vaccination against typhoid fever and, for epidemic indications, with polyvalent vaccines is carried out during mass epidemics. Bacteriophages are administered orally. Bacteriophage preparations are also used. The disease develops acutely in the initial stages, after a few days the stool becomes foul-smelling (“watery”, with greens), a large number of neutrophilic leukocytes are found in the stool, which are absent on the first day of the disease, and on the second day their number reaches 1 million/ml of feces , at subsequent stages the quantitative indicator decreases. In severe forms of the disease, stools may become very frequent and the stool may be watery, i.e. the patient has bowel movements after almost every meal. Also, patients with shigeloid intestinal infection experience vomiting, the temperature is usually 38 - 40 ° C, sometimes it normalizes for a short period, after which it rises again. Most often, the first signs of a dysentery infection are nausea, pain in the lower abdomen with effects around the navel, sometimes in the lower back, and symptoms of “stomach fullness.” Such phenomena are observed from two to five days, after which mucus or blood appears in the patient’s stool. This does not happen in healthy individuals. Gradually, the stool becomes less abundant, but if it is scanty, then there is a danger of dehydration, since fluid loss occurs along with