Fumagillin

Fumagillin is an antibiotic that was developed in the 1960s to treat tuberculosis. It was discovered by a team of scientists from the University of Toronto led by Dr. William J. Farrar.

Fumagillin was developed based on a natural antibiotic obtained from the fungus Fusarium solani. This fungus has been used to produce antibiotics since the 18th century, but fumagillin was the first synthetic antibiotic to be proven effective in treating tuberculosis.

After successful testing in animals, fumagillin began to be used in humans. In the 1970s, it became one of the most popular antibiotics in the world. However, in 1981 it was discovered that fumagillin can cause serious side effects such as allergic reactions and liver damage.

Today, fumagillin is not used in medicine due to its high toxicity and low effectiveness. However, it continues to be an object of scientific research, since its structure still remains complex and interesting to study.