Polyclonal gammopathy is a disease in which there is an increased level of immunoglobulins in the blood. It belongs to the category of autoimmune diseases and is characterized by impaired functioning of the immune system. One of the main causes of polyclonal gammopathy are various types of lymphoproliferative diseases, among which lymphoma and multiple myeloma are the most common. Other causes leading to this pathology include infectious diseases, allergic reactions, autoimmune diseases and some genetic disorders.
Symptoms of gammopathy may include fatigue, weakness, weight loss, enlarged lymph nodes, and the formation of tumors (tumor-like lesions) in various organs (most commonly the kidneys, bone marrow, and abdomen). When examining blood, signs of hypergammaglobinimia are observed - an increase in the level of immunoglobulin in the blood plasma. One of the most common symptoms is the periodic appearance of a body temperature above 37 degrees Celsius.
The main methods for diagnosing gammopathy are blood tests, including analysis for the presence of gammaglobulin immunoglobulin-containing proteins, analysis of their level in blood serum, and others. However, for a more accurate diagnosis it is necessary to conduct a number of additional studies.
Treatment for gammopathy can be medical or surgical. Drug treatment includes the use of hormonal drugs, cytostatics, immunosuppressants and other drugs. Surgery may involve removing the affected tissue or organs.
The prognosis of gammopathy depends on what treatment methods are used and how effectively the therapy is carried out. In some cases, symptoms