Gastrin (Gastrin)

Gastrin is a hormone produced by the mucous membrane of the pyloric region of the stomach. It plays an important role in regulating the digestive system.

Gastrin is produced by gastrin-secreting cells (G cells), which are located in the mucous membrane of the pyloric region of the stomach. The stimulus for gastrin secretion is the presence of food in the stomach. When food enters the stomach, the hormone is released into the blood and stimulates the stomach to secrete gastric juices.

Gastrin also increases intestinal motility, which helps food move through the digestive system. This hormone can also stimulate the release of other hormones such as somatostatin, which reduces the secretion of gastric acid.

The level of gastrin in the blood can vary depending on various factors, such as the level of acidity in the stomach and the presence of certain diseases, such as stomach ulcers and stomach tumors. It is also known that gastrin may play a role in the development of stomach cancer.

Overall, gastrin plays an important role in regulating the digestive system. Its release stimulates the stomach to secrete gastric juice and enhances intestinal motility. However, high levels of gastrin in the blood can indicate the presence of certain diseases, such as stomach ulcers and stomach cancer, so it is important to monitor its levels.



Gastrin is a key hormone produced by the pyloric mucosa of the stomach, also known as the G cell. This hormone plays an important role in regulating the digestive process. Gastrin is released in response to the presence of food in the stomach and affects various aspects of digestion.

When food enters the stomach, the mucous cells of the pyloric region begin to produce gastrin. This process is stimulated by physical and chemical signals associated with food intake. Gastric distension and the presence of dietary components such as proteins and amino acids promote G cell activation and increase gastrin secretion.

Gastrin circulates in the blood and exerts its effects on various organs of the digestive system. Mainly, it stimulates gastric secretion, which leads to increased secretion of gastric juice. Gastrin stimulates the secretion of hydrochloric acid and pepsin, substances necessary for the breakdown of food. This provides optimal conditions for digestion and absorption of nutrients.

In addition, gastrin affects intestinal motility. It enhances contractions of intestinal smooth muscles, promoting the movement of the food bolus along the digestive tract. This helps ensure efficient movement of food through the intestines and improves the process of peristalsis.

Disturbances in gastrin hormone levels can have various health consequences. High levels of gastrinoma may be associated with medical conditions such as peptic ulcers or tumors called gastrinomas. Low gastrin levels can lead to decreased stomach acidity and disruption of the digestive process.

In conclusion, gastrin plays an important role in regulating the digestive system. This hormone, produced by the mucous membrane of the pyloric region of the stomach, stimulates the secretion of gastric juice and enhances intestinal motility. Understanding the functions of the gastrinome helps us better understand digestive processes and may have practical implications in the study and treatment of digestive diseases.



Gastrin is a hormone produced by the mucous membrane of the pyloric region of the stomach (see G cell). The stimulus for gastrin secretion is the presence of food in the stomach. This hormone circulates in the blood and stimulates the secretion of gastric juice. In addition, gastrin enhances intestinal motility.

Thus, the main functions of gastrin are to stimulate the secretion of gastric juice and enhance peristalsis of the gastrointestinal tract. Gastrin plays an important role in the digestive process, providing optimal conditions for the digestion of food in the stomach and intestines. Elevated or decreased gastrin levels can lead to digestive disorders and other gastrointestinal diseases.