Tissue Acidosis

Type I tissue acidosis, Perman's disease, is a rare phenomenon. This is a tissue process that is associated with the formation of large amounts of bicarbonate, which causes an increase in blood alkalinity. The disease is accompanied by the appearance of congestion in the lower parts of the lungs, where blood fluid accumulates, similar to what happens with diseases of the pulmonary veins that leak into the circulatory system. In addition, the patient experiences bloating due to increased formation of organic acids. Often this acidosis is found in infants under one year of age and patients whose age does not exceed 25 years.

**Causes of this disease, its symptoms.** Most often, the disease is caused by a primary violation of the acid-base balance or a decrease in metabolic processes. There are more than a hundred forms of the disease, the most common are: 1. Acetoacetic acid - during the breakdown of which a large number of acid ions are formed, replacing bicarbonate ones; 2. Leukolytic type, caused by bedbug bites (causes a severe course); 3. Ischemic: caused by low oxygen efficiency in the heart cells. **How ​​to diagnose pathology.** To identify this condition, it is necessary to conduct the necessary laboratory tests. The patient exhibits an imbalance of substances formed during the metabolism of carbohydrates and a change in the concentration of glucose in the blood. Diagnostic methods also include determining the amount of volatile acids - acetoacetate and acetone. These indicators are taken directly from the oral cavity without the help of a catheter. **What kind of doctor is needed?**The disease is treated by a pediatric gastroenterologist; sick infants are diagnosed by a pediatrician. The analysis of bicarbonate levels is carried out by the biochemical laboratory and the endocrinology department. Diagnosis is carried out by a specialist who specializes in identifying organic disorders.

Therapy can be either general or local. In the general treatment of acidosis, patients are given intramoral infusions of sodium bicarbonate. Local therapy helps replenish the electrolyte balance through injections of sodium chloride. It is important to remember that due to the huge variety of factors in the onset of the disease, treatment is individual for each patient.