Hemolysis In-device

Intra-apparatus hemolysis is a pathological process in which red blood cells are destroyed in the heart-lung machine (CAB) during its operation. Hemolysis can be caused by various factors such as high blood flow rate, high blood pressure, presence of air bubbles in the system, etc.

Intra-apparatus hemolysis can have serious consequences for the patient, since the destruction of red blood cells leads to loss of oxygen and nutrients, which can cause hypoxia and other complications. In addition, intra-device hemolysis can lead to the formation of toxic breakdown products of red blood cells, which can cause tissue and organ damage.

To prevent intra-device hemolysis, it is necessary to follow certain rules for working with AIK. For example, the blood flow rate must be optimal, the pressure must be controlled, and the system must be clean and free of air bubbles. It is also necessary to regularly check the condition of the system and replace worn parts.

If intra-device hemolysis develops, it is necessary to immediately stop working with the AIK and take measures to eliminate the problem. If hemolysis cannot be corrected, system replacement or even blood transfusion may be required.

Thus, intra-device hemolysis is a serious problem in medicine and requires careful monitoring and prevention. Compliance with the rules of working with AIC, regular checking of the system and replacement of worn parts will help prevent the development of hemolysis and maintain the health of patients.

In-apparatus hemolysis: causes, consequences and prevention measures

Intravenous hemolysis (IAH) is a process of destruction of red blood cells that can occur in heart-lung machines during perfusion. Perfusion is a technique used in surgery and cardiology in which blood is removed from the patient's body and then circulated through an artificial machine, oxygenating and pumping the blood back into the body.

The causes of in-apparatus hemolysis can be varied. One of the main reasons is the mechanical effect on red blood cells during circulation through the device. Contact with machine surfaces that may have sharp edges or irregularities may cause red blood cell damage and subsequent destruction. In addition, the strong pulsatile movement of blood through the device can also promote hemolysis.

The consequence of intravenous hemolysis is the release of hemoglobin, which is usually found inside red blood cells. Hemoglobin can cause various negative effects in the body, including intoxication and tissue damage. Elevated levels of hemoglobin in the blood can also cause