General Adaptation Syndrome

General information.

General Adaptation Syndrome is an umbrella term used to describe a seemingly nonspecific class of adaptation disorders in various animals and humans, etiologically associated with chronic emotional or psychophysiological stressful conditions. In addition, general adaptive syndrome is a syndrome caused by intense training, such as training in sports, and combined with increased resistance. In addition to stress and training, a general adaptive syndrome can also be any neuropsychic stress that requires special adaptation of the body (for example, hibernation). The general adapted syndrome contains two components: a neuroendocrine or stress-reactive component and the actual adaptive or final level of reaction or adaptation achieved due to the previous stress-reactive component. Like any stress, the general adaptation syndrome contains the sympathetic-adrenal reaction and the hypothalamic-pituitary-adrenal reaction and causes an increase in the activity of the sympathoadrenal system, increases lipolysis and depletes glucose. Under favorable circumstances, it promotes the activity needed to cope with a stressor. At the same time, general adaptive behavior represents inhibition of basic natural drives (food, sexual), leading to exhaustion, and in some conditions, a suicide attempt. Normally, adaptation mechanisms are activated before stress occurs and require stimulation from autonomic or supralingual structures. This mechanism serves as the basis for the prevention of fatigue and adaptation to high loads.