Hypercorticism [Hypercorticismus; Hyper- + Cortico(Steroids)]

Introduction

Hypercortisolopenia, also known as hyper-cortisolopenia, is the general name for a group of syndromes and diseases whose main symptom is an excess of corticotropic hormones of the adrenal cortex in the blood (hyper-cortisolopenia). These hormones control the levels of other hormones such as sex hormones and pituitary hormones. They also participate



Today we will look at one of the most poorly understood diseases in medicine: hypercortisolism (Cushing's syndrome). Research carried out in this direction is focused on studying disorders of the neuroendocrine system. This is a set of studies on the causes of increased levels of steroid hormones, as well as their effect on body functions.

The essence of hypercortisolism is that the body produces too much cortisol, which is the main stress hormone and affects the biochemical processes of the body as a whole. Cortisol is actively involved in the regulation of blood pressure, heart and kidney function, removal of fluid and electrolytes from the body, metabolism, growth, development and formation of tissues and organs. However, excess cortisol can lead to adverse effects and even death with prolonged exposure.

Hypercortisolism can be caused by various diseases, such as an adrenal tumor that secretes large amounts of corti



Hypercorticosis is a set of disorders in the body that are caused by an increased concentration of corticosteroid hormones in the blood. The name comes from the Greek word “hyper” - “above”, “over” and the Latin word “corticus” - “adrenal cortex”. In the scientific literature, this term is also called Itsenko-Cushing syndrome. This syndrome is rarely observed in children. It is usually diagnosed when puberty begins and can be caused by two reasons: - hypersecretion of the adrenal glands; - suppression of the functions of the thyroid gland or - the hypothalamic-pituitary system.

In this regard, two types of syndrome are distinguished: primary and secondary. With the first, hormonal changes are observed in the adrenal cortex, with the second, their level increases due to a decrease in other hormones that affect their production. Cortisol (adrenal cortex hormone) can enhance the synthesis of serotonin, norepinephrine, and insulin. Consequences of a long course of the disease



_Hypercorticism is a word made up of two Greek roots: “hyper” means “too much,” and “corticos” can be translated as “periosteal” or “periosteal.” It turns out that this disease manifests itself not only in the adrenal glands, but also in the pituitary gland, which is why it was called adrenal hypercortisolism. Refers to endogenous (hormone-dependent) diseases. A distinctive feature of the disease is its high speed and severity of development, leading not only to a long-term comatose state of the patient, but also to personal disability.