Gliogranuloma

Gliogranuloma is a rare chronic inflammatory disease characterized by damage to the brain or spinal cord.

Gliogranulioma belongs to the group of odontogenic granulomatous tumors and is localized in the substance of the brain and spinal cord, leading to diffuse changes, hemorrhages, vascular changes and the formation of a tumor capsule.

The existence of gliogranulomas for a long time causes great difficulties in diagnosis and treatment. Issues of both diagnosis and surgical treatment remain controversial, partly due to the rarity of the disease. At the onset of the disease, damage to the upper part of the spinal cord (region T1-T3) is noted. Then there is damage to the base of the brain (T6-T7), medulla oblongata (T7-T8) and brain stem (C1-C2). Thus, there is a significant amount of changes in the central nervous system. An important role in the diagnosis of chronic brain diseases belongs to computed tomography or MRI of the brain and spine. If odontogenic gliogranutoma is suspected, it is necessary to carry out differential diagnosis with other diseases of the peripheral nerves and brain: syphilis, tuberculosis, central nervous system tumor, endocarditis, dissecting aneurysm, discirculatory encephalopathy.

Also, clinical tests of blood, urine, and feces are required to determine the patient’s condition with glioblastoma or glioblastomas.