Granulomatous disease caused by exposure to various species of Listeria monocytogenes. Transmission of infection occurs through direct contact with the mucous membrane or by eating contaminated meat.
This microorganism was discovered back in 1872 by R. Koch, who called it the “bacterium of death.” To date, many forms of the disease have been described. It is noted that the leading role in the occurrence of the disease belongs to poorly described and not typical species of L. monocytogenes, including entire subsections of strains that have different types of effects on the macroorganism.
Unlike other mycobacteria, mycoplasmas are exoaerobes. These are very fast microorganisms that are resistant to many drugs. Nitric oxide is known to have antimicrobial activity and interferon-induced alpha-2:alpha has antiviral activity in low concentrations, but is rapidly depleted by most drugs. On the other hand, virulent strains of L.monocytogenes are known, the resistance of which is insensitive to the action of known drugs. In such cases, it is necessary to use specially selected antibacterial therapy in accordance with a certain dose as treatment. At the same time, the probability of cure remains quite high.