Heparin

Heparin is a drug that is used to prevent and treat thrombosis and other cardiovascular diseases. In this article, we will look at the basics of heparin, how it works, and its medical uses.

Heparin was discovered in 1916 and became the first anticoagulant used for the treatment and prevention of thrombosis. After decades of research and development, it was approved by the US FDA in 2014. Today, heparin is widely used in medical practice for the treatment and prevention of blood clotting, since it is highly effective and low toxicity.

Heparin acts by inhibiting the coagulation cascade. The mechanism of action of heparin is by binding to coagulation factors (platelets, fibrinogen, plasminogen). This blockage leads to changes in the clotting system and slows down the formation of blood clots in the blood vessels.

It is important to note that heparin can have both positive and negative health effects. For example, heparin helps prevent heart attacks and strokes, but overusing it can lead to bleeding and life-threatening complications. Therefore, heparin should be used strictly under medical supervision and with a prescription.