Homovital graft

Homovital transplants are a group of biocompatible allogeneic or xenografts consisting of a fragment of the body of a donor, a person, whose tissue type remains the same as in the donor’s body. In this case, if a threat to life appears, such a group of tissues will be taken for emergency rescue of patients [1].

In fact,

Cardiopulmonary homovital transplantation was successfully performed for the first time in the world by Russian cardiac surgeons in 2017. Although the incidence of adverse outcomes after various types of lung transplantation is considered to be quite high - from 5 to 30%, the results of using all-homovital grafts in patients with severe malformations or irreversible lung failure appear to be much better than previously thought. **Homoviteral** is a characteristic of tissue that partially produces its own proteins and tissues and thus has low immunity. As a rule, the transplanted organ (lung or heart) is selected in such a way as to match each other as closely as possible, which reduces the number of complications and improves the prognosis for the patient. These methods make it possible to obtain complete compatibility between the donor organ and the recipient, but at the same time they are quite risky for patients and doctors, as they have a high risk of complications during the operation and recovery after it. In addition, lung transplantation is one of the most difficult types of transplantation in medicine, because... requires careful preparation of organs, as well as the use of additional tools, such as additional vessels and lungs. In general, Homovital heart transplant is the treatment of choice for severe heart and lung disease, but requires a high level of skill among surgeons, physicians and researchers to ensure the best results and reduce risks for patients. If done correctly, there is less chance of relapse than with a transplant, where the donor organ does not have the ability to produce its own biological materials, such as immune proteins or hormones.

The transplantation includes the following stages:

- Preparation for organ transplantation (selection of a suitable donor, preparation of the patient); - Performing surgery (explantation and organ harvesting, aorto-carotid anastomosis, organ implantation); - Accompanying the patient after surgery; - If necessary, repeated transplantation operations (aortic valve transplantation, endovascular therapy, foreign body removal, etc.).