Hopf Verrucous Acrokeratosis

Hopf acrokeratosis verrucous is a chronic disabling skin disease affecting the skin and internal organs.

The etiology of the disease is not completely clear; it is hereditary. Sometimes occurs among members of the same family. The cause may be exposure to trauma, severe overload



Hopf's disease, or Akkeratosis verrucous, is a rare genetic skin disease that appears as large bump-like growths on the skin and leads to severe itching and discomfort. Another name for the disease is Darier's gangrene, also known as epidermodysplasia verrucous.

Hopf's disease usually occurs in men and is rare in women. The disease is characterized by the development of large keratinized plaques that look like growths on the skin. These formations may be caused by genetic disorders in the cellular processes of the skin.

Hopf's symptoms include an itchy, erythematous rash that occurs on the hands and elbows, knees and legs. Often dust, dirt or sweat gets on the rash and it becomes even more inflamed. In some cases, increased dryness of the mucous membrane occurs due to lack of moisture in the skin. The so-called “acid rash” affects the upper layers of the dermis,