Kala-Azar Mediterranean Children's

Kala-azar (kala-azakhr, Central Asian disease) is a parasitic disease caused by a virus from the Chlamydiae family, characterized by a slow progressive course with damage to the liver, spleen, lymph nodes and other organs, as well as the development of inflammatory infiltrates in them. In adolescent children, it manifests itself as an acute onset with high fever, malaise, catarrhal symptoms, and involvement of the liver and lymphatic system in the pathological process. The diagnosis is based on the detection of leishmanial Burnett's bodies in the blood, puncture of affected organs, and urine. Treatment is carried out with antimalarial drugs, such as delagil and others. A typical sign of kala-azar is gummous ulcers. Cases of the development of leishmaniasis within 5 years after treatment with local remedies have been described.

Kala-azar is an acute protozoal disease caused by the parasite Leishmania tropica mediterranea (Leishmania tropica ssp. mediterraneorum). Kala-azor is one of the most common diseases of the liver and spleen in countries with hot climates, especially in Mediterranean and central Asia. The disease is usually observed among young children. Kala-azar infection is more common in children aged 2 to 5 years. The incubation period for kala-azar infection ranges from several days to several weeks. Patients may not experience any symptoms until the first signs of fever and weakness, and then problems with the liver and pancreas begin. Damage to the splenic vein can lead to dangerous bleeding. The death of a child as a result of kala-azaria can be sudden and rapid.

To diagnose kala-azor, it is necessary to conduct a general blood test, where an increase in leukocytes and erythrocyte sedimentation rate will be visible. If the patient has signs of fever, testing for markers of fecal infection, such as Leishmania blood antibodies, should be done. Chronic inflammation of the lymph nodes may indicate the onset of the disease. Treatment for kala-azara should be started as early as possible to avoid complications from the liver and pancreas. Chemotherapy includes taking drugs from the group of sulfonamides, alkaloids, penicillins and antimicrobial drugs such as sodium isotyrosine.