Kallikrein

Kallikrein is a member of a group of enzymes present in the blood and other body fluids that affect a number of plasma globulins, leading to the formation of bradykinin and kallidin.

Kallikrein is a proteolytic enzyme capable of breaking down proteins. It catalyzes the conversion of kininogen (an inactive precursor of kinins) into biologically active peptides - bradykinin and kallidin. These substances are mediators of inflammation, they dilate blood vessels, increase their permeability, and stimulate pain.

Kallikrein plays an important role in the regulation of blood pressure, inflammatory reactions, and blood clotting processes. Disturbances in the kallikrein-kinin system are associated with the development of hypertension, edema, allergies and other pathological conditions.

Thus, kallikrein is a blood plasma enzyme involved in the formation of biologically active peptides that regulate blood pressure, inflammation and other processes in the body. Violation of its functions leads to pathologies.



**Kallikreins** are enzymes that can convert substrates into various products when hydrogen ions are added. They are widespread in nature and play an important role in the human body. This group of enzymes is represented by a number of species that differ in structure and function. One such type of kallikrein, called kallidin, can be converted into bradykinin. Callicin exhibits a similar function, although it is somewhat different from kallidin kallikranin in the production of bradykinins. Bradykinin is a powerful biological agent that is involved in many important processes in the body, such as the regulation of blood pressure, heart rate and inflammation.



Kallikreins are a group of enzymes responsible for many functions in the body. One of them - Kallikrein - is an important part of the hemostatic regulation system. As an enzyme, Kallikreins has a complex structure and complex mechanism of functioning that make it unique for its medicinal uses.