Complement C3

Complement C3 is one of the main components of the complement system, which plays an important role in protecting the body from infections and other pathogens. Complement consists of many proteins that interact with each other to create a protective response in the body.

Complement C3 is a protein found in the blood that is involved in reactions related to the body's immune response. It is one of the components of the complement system and is responsible for activating this system upon contact with infectious agents.

Upon contact with an infectious agent, complement C3 is activated and converted into a complex called “C3 convertase.” This complex catalyzes the cleavage of complement C3 into two molecules: C3a and C3b.

C3a is a chemotactic factor and plays a role in attracting leukocytes to the site of inflammation. C3b binds blood clotting factors, which promotes the formation of blood clots and stops bleeding.

In addition, complement C3 can activate other components of the complement system, such as C5 and C9. This can lead to the formation of reactive oxygen and nitrogen species, which can kill bacteria and other infectious agents.

Thus, complement C3 plays an important role in the body's immune response and protection against infections. Its activation and cleavage into C3a and C3b can lead to various biological effects such as the attraction of white blood cells and the formation of blood clots.

Introduction: Complement is a group of proteins in the blood plasma of humans and animals that are involved in the body’s immune defense against infections. Complement consists of several components, including the c3 protein, which is one of the main components.

Description of component C3: C3 is the fourth complementary protein - a blood coagulation factor that completes the activation system of human serum. The active principle is the proteolytic cleavage of the polypeptide chain of factor C302 and the X-X-linked self-accelerating formation of the 2+ complex. C3 realizes the chemotactic and antibacterial properties of serum, saturability, high affinity, and the indirect bactericidal effect of the membrane adhesion factor QoQ. The reaction component limits the effect of all other alternatively activated complement components C2C3CC5C6C7 and does not participate in pore formation reactions. The ability to initiate and escalate the antimicrobial immune response in mammals and the presence of chemoattractant receptors on the cells of the nervous system determine the basic significance of the C3 component. It is produced in various infectious diseases by lymphocytes in internal organs - MPS and CMV cells, HHV macrophages, TL, cell tumors, tubular carcinoma with various etiological properties of malignant neoplasms of the kidney, bladder, and stomach. With the natural development of inflammatory processes involving hemolytic streptococcus, patients with chronic polyarthritis and vascular thrombosis become a risk group for the formation of hypersplenism. Given the similarities, they woke up